Primary and Secondary Metabolites

Most plants, fungi and other microbes synthesizes a number of organic compounds called as metabolites which are intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. It can be catergorized into two types namely primary and secondary metabolites based on their role in metabolic process (Figure 8.4).

 Synthesis of metabolites during growth
Synthesis of metabolites during growth

Primary metabolites are those that are required for the basic metabolic processes like photosynthesis, respiration, protein and lipid metabolism of living organisms.

Secondary metabolites does not show any direct function in growth and development of organisms.

Morphine is the first alkaloid to be found. It comes from the plant Opium poppy (Papaver somniferum).

Metabolites Examples
Primary
Enzymes protease, lipase, peroxidase
Amino acid proline, leucine
Organic acid acetic acid, lactic acid
Vitamins A, B, C
Secondary
Pigments carotenoids, anthocyanins
Alkaloids morphine, codeine
Essential oil lemon grass oil, rose oil
Toxins abrin, ricin
Lectins concanavalin A
Drugs vinblastin, curcumin
Polymeric substances rubber, gums, cellulose

Organic Molecules

Organic molecules may be small and simple. These simple molecules assemble and form large and complex molecules called macromolecules. These include four main classes – carbohydrates, lipids, proteins and nucleic acids. All macromolecules except lipids are formed by the process of polymerisation, a process in which repeating subunits termed monomers are bound into chains of different lengths. These chains of monomers are called polymers.


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